In recent years, saliva testing has emerged as a powerful tool for monitoring and managing mental health, particularly in the realm of stress, anxiety, and burnout.  This non-invasive method offers a wealth of information about an individual’s physiological state, providing valuable insights for personalized mental health interventions. The Science of Salivary Biomarkers Saliva contains a […]

In the ongoing battle against obesity and its associated health risks, researchers and healthcare professionals are constantly seeking innovative methods for early detection and prevention. One such breakthrough comes in the form of saliva-based testing, which has emerged as a promising tool for predicting metabolic health risks, particularly in relation to obesity.  This non-invasive approach […]

Personalized nutrition has emerged as a groundbreaking approach to optimizing individual health through tailored dietary recommendations. As we delve deeper into the intricate connections between our bodies and the food we consume, an unexpected player has entered the game: saliva.  Saliva, which is often overlooked, holds the key to unlocking a wealth of information about […]

Non-communicable diseases (NCDs) such as diabetes, cardiovascular disease, cancer, and chronic respiratory conditions are among the leading causes of death globally. Unlike infectious diseases, NCDs often develop slowly, making early detection and ongoing monitoring critical for effective management. Yet, as highlighted by The Lancet Commission on Diagnostics, significant diagnostic gaps persist in the care pathways […]

Global health security has become a pressing priority. From the COVID-19 pandemic to the ongoing challenges of antimicrobial resistance, the need for accessible, accurate, and equitable diagnostics has never been more apparent.  Diagnostics are not just a tool for detecting disease—they are a cornerstone of effective healthcare systems, enabling early intervention, guiding treatment, and preventing […]

Saliva-based diagnostics are rapidly emerging as a revolutionary tool in healthcare, offering a non-invasive, cost-effective, and accessible alternative to traditional diagnostic methods. As healthcare systems worldwide strive to improve patient outcomes and expand access to testing, saliva-based diagnostics are proving to be a transformative solution, particularly in the realm of point-of-care (POC) testing. This innovative […]

Access to healthcare remains a global challenge, with marginalized communities—such as rural populations, low-income households, and underserved groups—facing the greatest barriers.  One of the most significant hurdles in healthcare is diagnostic access. For many, the journey to receive a diagnosis involves long travel distances, high costs, stigma, and inadequate infrastructure.  However, self-sampling technologies, particularly saliva-based […]

The field of diagnostics is being transformed by multiplex detection in saliva tests. With the ability to detect multiple biomarkers simultaneously, multiplex lateral flow immunoassay (LFIA) technology is expanding the boundaries of what saliva-based diagnostics can achieve. This innovation is enhancing efficiency, reducing testing time, and opening up new possibilities for disease monitoring and management. […]

Monitoring hormones is essential for understanding and managing various aspects of health, from stress to fertility. Traditionally reliant on invasive blood tests, hormone tracking has taken a significant leap forward with saliva-based testing, powered by lateral flow immunoassay (LFIA) technology. This innovative approach is making hormone monitoring more accessible, convenient, and accurate than ever before. […]

Point-of-care diagnostics is undergoing a transformative shift, and portable saliva tests are at the forefront of this revolution. Powered by lateral flow immunoassay (LFIA) technology, these compact, user-friendly devices enable rapid diagnostics in critical healthcare settings. By offering timely results and requiring minimal training, portable saliva tests are improving response times in emergencies, optimizing patient […]

The COVID-19 pandemic reshaped the global healthcare landscape, driving unprecedented advancements in diagnostic technologies. Among the many innovations, saliva-based testing technologies experienced significant growth, fueled by the demand for non-invasive, rapid, and accessible diagnostic solutions. Lateral flow immunoassay (LFIA) technology became a cornerstone in the fight against COVID-19, enabling effective saliva-based tests that set new […]

Home diagnostics are undergoing a revolutionary shift, with saliva-based rapid testing taking center stage. These tests, powered by lateral flow immunoassay (LFIA) technology, offer unprecedented convenience and reliability, allowing individuals to monitor their health from the comfort of their homes. From detecting infectious diseases to managing chronic conditions, saliva-based diagnostics are paving the way for […]

The ability to track hormones has revolutionized how we understand and manage stress, fertility, and other endocrine functions. Saliva-based hormone testing, powered by lateral flow immunoassay (LFIA) technology, is at the forefront of this transformation. This approach offers a convenient, accurate, and non-invasive alternative to traditional blood tests, making hormone monitoring more accessible than ever […]

Cardiac troponin (cTn) is the biomarker of choice for detection of myocardial injury. There is a great need for simple point-of-care (POC) troponin testing among patients with chest pain, mainly in the prehospital setting. The purpose of this study was to evaluate the presence of cardiac troponin I (cTnI) in saliva of patients with myocardial […]

As saliva emerges as a vital diagnostic tool, the importance of proper collection and preservation methods cannot be overstated. Saliva is a rich medium containing a variety of biomarkers—DNA, RNA, proteins, metabolites, and hormones—yet its diagnostic potential hinges on maintaining the stability of these components from collection to analysis.  Innovations in saliva collection and preservation […]

Saliva is proving to be a goldmine for modern diagnostics, and the emerging field of salivary metabolomics is taking its potential even further. By analyzing the small molecules, or metabolites, in saliva, researchers can uncover valuable insights into a person’s health, diet, and exposure to environmental factors.  This non-invasive approach is opening up new pathways […]

Saliva is emerging as a powerful medium for understanding the impact of environmental and lifestyle factors on human health. At the heart of this potential is DNA methylation—a key epigenetic modification that alters gene expression without changing the DNA sequence. Recent research has shown that saliva, being rich in both human and microbial DNA, provides […]

Saliva is redefining the future of diagnostics. It is now proving its worth as a non-invasive, rich, and accessible medium for detecting diseases.  Its ability to replace or complement blood tests is poised to revolutionize healthcare, making diagnostics more patient-friendly and efficient.  Here’s how saliva is making waves in the diagnostic field. The Comfort and […]

Aging is a universal process, but its effects on the body remain a complex puzzle. Among the emerging tools for understanding this journey, saliva stands out for its simplicity and diagnostic power. This unassuming fluid, rich in proteins and biomarkers, reflects biological changes that occur as we age.  By analyzing proteins like prolactin inducible protein […]

Saliva, which is typically overlooked in clinical settings, is emerging as a powerful tool for understanding health. Packed with proteins, enzymes, and other biomarkers, it reflects the body’s physiological state in real time.  Among the standout components are transferrin and prolactin inducible protein (PIP), which are now recognized for their roles in personalized health diagnostics. […]

Saliva, once overlooked as a simple bodily fluid, is gaining recognition as a diagnostic goldmine.  Its composition provides insights into the physiological differences between genders and helps pave the way for personalized healthcare. Among its components, proteins like β-2-microglobulin and transferrin offer clues about the unique immune and metabolic dynamics of men and women.  These […]

A single drop of saliva contains a wealth of information, especially for patients with autoimmune diseases like Sjögren’s syndrome (SS). Among the many changes SS induces in the salivary glands, alterations in electrolyte levels—specifically calcium (Ca²⁺), chloride (Cl⁻), and potassium (K⁺)—stand out as key indicators of the disease’s impact.  These hidden signals not only reflect […]

Oral health has long been considered a mirror of overall health, and for patients with autoimmune diseases like Sjögren’s syndrome (SS), this connection runs even deeper. SS, an autoimmune disorder that primarily targets moisture-producing glands, has profound effects on the oral cavity, leading to decreased saliva production and altered salivary composition. But beneath these symptoms […]

In the realm of medical diagnostics, visibility is power. Yet, when it comes to complex autoimmune diseases like Sjögren’s syndrome, the critical biomarkers often remain shrouded, hidden beneath layers of more dominant proteins. Recent advances in protein depletion technologies are changing the game, allowing researchers to peer deeper into saliva samples and unlock a wealth […]

When most people think of autoimmune diseases, the diagnostic journey often conjures images of invasive blood tests and lengthy medical evaluations. Yet, groundbreaking research is revealing that something as simple as a saliva sample could hold answers to some of medicine’s most complex conditions, like Sjögren’s syndrome (SS).  This autoimmune disorder, affecting nearly a million […]

For decades, blood tests have been the gold standard for diagnosing and monitoring health conditions. But what if there was a way to gain similar, if not better, insights without the needle? Saliva testing, powered by recent technological breakthroughs, is proving to be a viable—and often superior—alternative in certain diagnostic scenarios. The Unique Edge of […]

Beneath the unassuming surface of saliva lies a goldmine of diagnostic potential.  Scientists have long explored its utility as a window into health, and recent advances in proteomics are bringing us closer to realizing its full potential. By delving into the nuances of saliva’s protein composition and overcoming technical hurdles, researchers are unlocking unprecedented capabilities […]

Blood tests are the gold standard for health diagnostics, but saliva testing is quickly emerging as a complementary tool with unique advantages. Saliva-based diagnostics offer a non-invasive way to track health, requiring only a simple mouth swab rather than a needle. However, saliva testing is still in its early stages, with a long way to […]

Saliva testing is gaining attention as a powerful tool for health monitoring, offering a non-invasive alternative to traditional blood tests. However, in its current form, saliva testing is just beginning to scratch the surface of what’s possible.  Researchers are now exploring advanced techniques to remove specific proteins that crowd the “salivary proteome”—the collection of proteins […]

Saliva has long been recognized as a valuable biofluid for the diagnosis and monitoring of various health conditions. Its non-invasive collection and the broad spectrum of biomarkers it contains, mirroring those found in blood, make it an ideal candidate for clinical use.  However, the high abundance of certain proteins in saliva, such as alpha-amylase, can […]